David Sebba was born in Israel. He was awarded M.Mus in composition and singing from the Tel Aviv University's Rubin Academy of Music with Excellence. He composed theatre music, wrote arrangements and orchestrations, and sang solo roles with most of the orchestras and choirs in Israel. He won scholarships from the America-Israel Cultural Foundation, the MOST Foundation, the Israeli Opera and the Israel Vocal Arts Institute. He won the first prize of the Academy's voice competition. He was a member of the staff at the School for Choral Singing and Alon School's acting class. He participated in many productions of the Israeli Opera as a pianist and soloist. He has translated many operas, among which are "Mahagonny", "Billy Budd", "Die Fledermaus", "Carmen", "Il barbiere di Siviglia", "Cenerentola", "L'elisir d'amore", "Die Zauberflöte", "Noah's Flood" and more.
He participated a few times as a vocal coach in the Ticino-Musica annual summer courses in Switzerland and performed in many concert tours abroad as a pianist, singer and conductor. In 2003 he established the operatic ensemble OddOpera. These days he is the Conductor in Residence of the Raanana Symphonette Orchestra and serves as a music director of three choirs. He is also in charge of the opera class at the Jerusalem Music Academy, participates in choral festivals in Europe and in recordings for radio and television and performs in operas and concerts as a conductor, singer and accompanist. During the last two years he regularly performs his own show Mad about Opera, a parody about the history of voice and opera, accompanied by pianist Irit Rub.
He wrote the words and music to the opera Alice in Wonderland commissioned by the Israeli Opera and conducted performances of this work both at the opera house and all around Israel. He also wrote the words and composed the music to the chamber opera Mothers which deals with the lead mother characters in the Biblical history of the Jewish people.